| Cefazolin is an antibacterial compound derived from 7-amino-cephalosporanic acid. Cefazolin is a broad-spectrum antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria. It is an effective cephalosporin antibiotic against both aerobic and anaerobic bacteria. Cefazolin is used in clinical isolates to inhibit the growth of methicillin-resistant staphylococcus, resistant microorganisms, and systemic inflammation. Some studies has shown good results to inhibit tumor necrosis factor-alpha (TNFalpha) production in cell culture. Synonyms: (6R,7R)-3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (6R-trans)-3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, 3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[2-(1H-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, 7-(1-(1H)-Tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]-delta3-cephem-4-carboxylic Acid, 7-(1H-Tetrazol-1-ylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic Acid, CEZ, Cefamezin, Cefaprim, Cefazolin, Cefazoline, Cephamezine, Cephazolin, Cephazoline, Elzogram, Sefazol, Zinol CAS No: 25953-19-9 Molecular Formula: C14H14N8O4S3 Molecular Weight: 454.51 Appearance: White to off-white solid Purity: 95% 1H-NMR Spectrum: Conforms to reference Melting Point: 185-188C (dec.) Storage and Stability: Store at -20C. Hygroscopic, under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
