| Chloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Chloroquine is are an schizonticidal agent and is a widely prescribed antimalarial compound. The antiviral activity of chloroquine in vitro has been reported in 1960s and recent publications have brought attention to its possible benefits in the treatment of COVID-19 patients, infected with the newly emerged coronavirus (SARS-CoV-2). Current evidence shows that chloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and the glycoprofile on the S-glycoprotein. Synonyms: N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine, ()-Chloroquine, 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline, Aralen, Artrichin, Bipiquin, Capquin, Chloraquine, Chlorochin, Chlorolex, loquin, E-Vivax, Hcqs, Maliago, NSC 187208, Nivaquinp, Premoquine, RP 3377, Reumachlor, Ronaquine, Rosq, ST 121, ST 121 (Pharmaceutical), Sequin CAS No: 54-05-7 Molecular Formula: C18H26ClN3 Molecular Weight: 319.87 Purity: 98% (HPLC) Appearance: White to light yellow powder Melting Point: 89-93C Specific Rotation: -1.0 to +1.0 deg (C=1, methanol) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. Stable for 6 months after receipt. Under inert atmosphere |
