Guanabenz Acetate, CAS [[23256-50-0]]

Product Overview

• Article Name: Guanabenz Acetate, CAS [[23256-50-0]]
• Biozol Catalog Number: USB-451505
• Supplier Catalog Number: 451505
• Alternative Catalog Number: USB-451505-100,USB-451505-500
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Guanabenz Acetate is an alpha-adrenoreceptor agonist that is used as an antihypertensive agent. A cell-permeable a2-adrenoceptor agonist that lowers protein misfolding in stressed cells (EC50 ~400nM in tunicamycin treated HeLa cells) and acts as a proteostatis regulator. Shown to selectively bind PPP1R15A/GADD34 and disrupt the PPP1R15A-PP1c complex, sustain eIF2a phosphorylation and increase chaperone availability by attenuating translation. Synonyms: [(2,6-Dichlorobenzylidene)amino]guanidine Monoacetate, 2-[(2,6-Dichlorophenyl)methylene]hydrazinecarboximidamide Monoacetate, 1-(2,6-Dichlorobenzylideneamino)guanidine Acetate, BR 750, Guanabenz Acetate, Guanabenz Monoacetate, Rexitene, Tenelid, Wy 8678 Acetate, Wytens, Wytensin, [(2,6-Dichlorobenzylidene)amino]guanidine Acetate CAS Number: 23256-50-0 Free Base: 5051-62-7 Molecular Formula: C10H12Cl2N4O2 Molecular Weight: 291.33 Appearance: White to Pale Yellow Solid Melting Point: 187-189C Solubility: Acetone (Slightly), DMF (Slightly), DMSO (Slightly), Methanol (Slightly) Storage: Hygroscopic, -20C Freezer, Under inert atmosphere

Product Properties

• Molecular Weight: 291.33
• Form: Supplied as a Pale Yellow Solid
• CAS Number: [23256-50-0]