KD 025 is an inhibitor of Rho-associated protein kinase II (ROCK-II), a serine/threonine kinase that regulates the formation of actin stress fibers and focal adhesions, smooth muscle contraction, and gene expression (1, 2). KD025 has been shown to reduce infarct volume after transient middle cerebral artery occlusion (2). Molecular Formula: C26H24N6O2 Solubility: Methanol (Slightly) Molecular Weight: 452.51 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
452.51
Form:
Supplied as a Off-White to Pale Yellow Solid
CAS Number:
[911417-87-3]
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