KRN 633 is an ATP-competitive inhibitor of vascular endothlial growth factor receptor tyrosine kinase (VEGFR). KRN 633 also suppresses VEGF-dependent activation of MAPK and cell proliferation and demonstrates antitumor and antiangiogenic activity by inhibiting vessel formation and vascular permeability in human tumor xenograft models. Molecular Formula: C20H21ClN4O4 Solubility: Chloroform (Slightly, Heated), DMSO (Slightly) Molecular Weight: 416.86 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
416.86
Form:
Supplied as a Off-White Solid
CAS Number:
[286370-15-8]
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