L-Methionine [R,S]-Sulfoximine-13C5,15N is the isotope labelled analog of L-Methionine [R,S]-Sulfoximine. Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM). Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinsons disease. Molecular Formula: 13C5H12N2O3S Solubility: Water (Slightly) Molecular Weight: 185.19 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
185.19
Form:
Supplied as a White Solid
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