| Lamivudine-13C1,d2, is the labeled analogue of Lamivudine. A reverse transcriptase inhibitor. Antiviral. Synonyms: 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone- 13C1,d2, (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)- pyrimidinone-13C1,d2, (-)-2-Deoxy-3-thiacytidine-13C1,d2, (-)-BCH 189-13C1,d2, 3TC-13C1,d2, Epivir HBV-13C1,d2, Hepitec-13C1,d2, Heptodin-13C1,d2, Heptovir-13C1,d2, L-SddC-13C1,d2, Lamivir-13C1,d2, Virolam-13C1,d2, Zeffix-13C1,d2, beta-L-2,3-Dideoxy-3-thiacytidine-13C1,d2, beta-L-3-Thia-2,3-dideoxycytidine-13C1,d2 Molecular Formula: C713CH9D2N3O3S Molecular Weight: 232.26 Form: Off-white solid Molecular Weight: 232.26 Purity: Chemical Purity: 95% Isotopic Purity: 98% Solubility: DMSO (slightly), Methanol (very slightly) Atmosphere: Inert gas Melting Point: >118C (dec.) Specific Rotation: -127.5 (c=1, Methanol) Method for Determining Identity: Proton NMR (DMSO-d6), C-13 NMR (DMSO-d6) and MS TLC Conditions: SiO2, Dichloromethane : Methanol (8 : 2). Visualized with UV and KMnO4 (single spot, Rf = 0.35). Storage and Stability: Store at -20C under inert atmosphere. Caution: Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
