m-Toluenesulfonyl Chloride was used as a reagent in the synthesis of sulfone hybrid scaffolds which displayed beta-glucuronidase inhibitory potential. Also used in the synthesis of arylmenthols via radical arylation of isopulegol. m-Toluenesulfonyl chloride may be used in the synthesis of mesityl-m-tolyl sulfone via reaction with mesitylene. Reactant involved in they synthesis of biologically active molecules including: Small molecule ligands for the Stat3 SH2 domain Isoindoline-5-propenehydroxamates for use as histone deactylase inhibitors Phenyl-pyrazolylamine-based derivatives as FLT3 kinase inhibitors Aryldisulfonamides with antibacterial activity Quinazoline analogs for the treatment of Gaucher disease 17beta-HSD2 inhibitors for the treatment of osteoporosis Synonyms: 3-Methylbenzenesulfonyl Chloride, 3-Methylbenzene-1-sulfonyl Chloride, Toluene-3-sulfonyl Chloride, m-Methylbenzenesulfonyl Chloride, m-Toluensulfonyl Chloride, m-Tolylsulfonyl Chloride CAS No: 1899-93-0 Molecular Formula: C7H7ClO2S Molecular Weight: 190.65 Appearance: Clear colorless oil Purity: 97% Refractive Index (n20/D): 1.5490 (lit.) Boiling Point: 252-253C(lit.) Density: 1.314g/ml at 25C (lit.) Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly) Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic, keep under inert atmosphere. Warning: Corrosive, Moisture Sensitive
Molecular Weight:
190.65
Purity:
97%
Form:
Clear colorless oil
CAS Number:
[1899-93-0]
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