N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester, CAS [[1874196-88-9]]

Product Overview

• Article Name: N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester, CAS [[1874196-88-9]]
• Biozol Catalog Number: USB-457591
• Supplier Catalog Number: 457591
• Alternative Catalog Number: USB-457591-10,USB-457591-25
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester is an intermediate in synthesizing PSI-7977-D5 (P839643), an isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2-deoxy-2-alpha-fluoro-beta-C-methyluridine-5-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Molecular Formula: C18H16D5N2O7P Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol Molecular Weight: 413.37 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 413.37
• Form: Supplied as a Pale Yellow Oil
• CAS Number: [1874196-88-9]