N-[[P(S),2R]-2-deoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-fluoro-2-methyl-P-phenyl-5-uridylyl]-L-alanine-d5 1-Methylethyl Ester

Product Overview

• Article Name: N-[[P(S),2R]-2-deoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-fluoro-2-methyl-P-phenyl-5-uridylyl]-L-alanine-d5 1-Methylethyl Ester
• Biozol Catalog Number: USB-457629
• Supplier Catalog Number: 457629
• Alternative Catalog Number: USB-457629-500,USB-457629-1
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

N-[[P(S),2R]-2-deoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-fluoro-2-methyl-P-phenyl-5-uridylyl]-L-alanine-d5 1-Methylethyl Ester is an intermediate in synthesizing PSI-7977-D5, an isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2-deoxy-2-alpha-fluoro-beta-C-methyluridine-5-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Molecular Formula: C28H38D5FN3O9PSi Solubility: Chloroform, Dichloromethane, Ethyl Acetate Molecular Weight: 648.74 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 648.74
• Form: Supplied as a White Solid