N-[[P(S),2R]-2-deoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-fluoro-2-methyl-P-phenyl-5-uridylyl]-L-alanine 1-Methylethyl Ester, CAS [[1256490-54-6]]

Product Overview

• Article Name: N-[[P(S),2R]-2-deoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-fluoro-2-methyl-P-phenyl-5-uridylyl]-L-alanine 1-Methylethyl Ester, CAS [[1256490-54-6]]
• Biozol Catalog Number: USB-457630
• Supplier Catalog Number: 457630
• Alternative Catalog Number: USB-457630-2.5,USB-457630-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

N-[[P(S),2R]-2-deoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-fluoro-2-methyl-P-phenyl-5-uridylyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate, which is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2-deoxy-2-alpha-fluoro-beta-C-methyluridine-5-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Molecular Formula: C28H43FN3O9PSi Solubility: Chloroform, Dichloromethane, Methanol Molecular Weight: 643.71 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 643.71
• Form: Supplied as a White Solid
• CAS Number: [1256490-54-6]