Octyl-alpha-hydroxyglutarate is a cell-permeable derivative of 2-HG (alpha-hydroxyglutaric acid). Mutations in isocitrate dehydrogenase 1 (IDH1 and IDH2) associated with certain cancers cause isocitrate to metabolize into 2-HG as opposed alpha-ketoglutarate, inhibiting alpha-ketoglutarate-dependant dioxygenases including lysine demethylases and DNA hydroxylases. This compound is suitable for IDH (isocitrate dehydrogenase) related research. Molecular Formula: C13H24O5 Molecular Weight: 260.33 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
260.33
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