(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol, CAS [[127852-28-2]]

Product Overview

• Article Name: (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol, CAS [[127852-28-2]]
• Biozol Catalog Number: USB-463653
• Supplier Catalog Number: 463653
• Alternative Catalog Number: USB-463653-5,USB-463653-25
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol is an intermediate in the synthesis of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. Molecular Formula: C10H8F6O Molecular Weight: 258.16000000000003 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 258.16
• CAS Number: [127852-28-2]