Regorafenib (Pyridine)-N-oxide, CAS [[835621-11-9]]

Product Overview

• Article Name: Regorafenib (Pyridine)-N-oxide, CAS [[835621-11-9]]
• Biozol Catalog Number: USB-464563
• Supplier Catalog Number: 464563
• Alternative Catalog Number: USB-464563-10,USB-464563-100
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib and is used for treatment and prevention of cancer. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRbeta, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5nM, respectively. Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 1-Oxide CAS No: 835621-11-9 Molecular Formula: C21H15ClF4N4O4 Molecular Weight: 498.81 Appearance: White to off-white solid Purity: As reported Melting Point: 223-227C Solubility: DMSO (Slightly), Methanol (Slightly, Heated) Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 498.81
• Purity: As reported
• Form: White to off-white solid
• CAS Number: [835621-11-9]