TPCA-1 is a direct dual inhibitor for both IKKbeta (IKK-2) and STAT3. It inhibits STAT3 phosphorylation, DNA binding, and transactivation in vivo. Synergistic treatment of TPCA-1 with tyrosine kinase inhibitors (TKIs) can potentially be a more effective method for treating cancers. Molecular Formula: C12H10FN3O2S Solubility: DMSO (Slightly), Methanol (Slightly) Molecular Weight: 279.29000000000002 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
279.29
Form:
Supplied as a Pale Beige Solid
CAS Number:
[507475-17-4]
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