H3N2-HA1, Influenza A virus (H3N2), Canine, aa18-344, His-Tag (Hemagglutinin Antigen, Hemagglutinin)

Catalog Number: USB-470233
Article Name: H3N2-HA1, Influenza A virus (H3N2), Canine, aa18-344, His-Tag (Hemagglutinin Antigen, Hemagglutinin)
Biozol Catalog Number: USB-470233
Supplier Catalog Number: 470233
Alternative Catalog Number: USB-470233-50,USB-470233-250
Manufacturer: US Biological
Category: Molekularbiologie
H3N2-HA1, also known as hemagglutinin antigen, is a subtype of viruses that causes influenza (flu). H3N2 Viruses can infect birds and mammals. In birds, humans, and pigs, the virus has mutated into many strains. It is increasingly abundant in seasonal influenza. This protein binds to sialic acid receptors on the cell surface, allowing viral particles to attach to cells. It plays an important role in host range restriction and toxicity determination, and mediates the penetration of virus into the cytoplasm by mediating the fusion of endosomal membrane and membrane. Recombinant protein corresponding to aa18-344 from Influenza A Virus (H3N2, canine), fused to His-Tag at C-terminal, expressed in Insect Cell. Molecular Weight: ~36.9kD (336aa) ~40-57kD (SDS-PAGE under reducing conditions) Amino Acid Sequence: ADPNLPGNEN NAATLCLGHH AVPNGTIVKT ITDDQIEVTN ATELVQNSST GKICNNPHKI LDGRDCTLID ALLGDPHCDV FQNETWDLFV ERSNAFSNCY PYDVPDYASL RSIVASSGTL EFITEGFTWA GVTQNGGSGA CKRGPANGFF SRLNWLTKSG NTYPVLNVTM PNNNNFDKLY IWGVHHPSTN QEQTSLYIQA SGRVTVSTRR SQQTIIPNIG SRPLVRGQSG RISVYWTIVK PGDVLVINSN GNLIAPRGYF KMRIGKSSIM RSDAPIDTCI SECITPNGSI PNEKPFQNVN KITYGACPKY VKQNTLKLAT GMRNVPEKQT HHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 36.94057
NCBI: 45177
UniProt: E2E3B0
Purity: 90% (SDS-PAGE). Endotoxin: 1EU/ug (LAL).
Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.