AIRE (Autoimmune Regulator), Rabbit

Product Overview

• Article Name: AIRE (Autoimmune Regulator), Rabbit
• Biozol Catalog Number: USB-474965
• Supplier Catalog Number: 474965
• Alternative Catalog Number: USB-474965-100
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Immunogen: Synthetic peptide corresponding to the N-terminal region of human AIRE

Product Description

The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• NCBI: 000374
• UniProt: O43918
• Purity: Purified by affinity chromatography.
• Form: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.