AIRE (Autoimmune Regulator), Rabbit

Product Overview

• Article Name: AIRE (Autoimmune Regulator), Rabbit
• Biozol Catalog Number: USB-474966
• Supplier Catalog Number: 474966
• Alternative Catalog Number: USB-474966-100
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Immunogen: Synthetic peptide corresponding to the N-terminal region of human AIRE

Product Description

AIRE is a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• NCBI: 000374
• UniProt: O43918
• Purity: Purified by Protein A affinity chromatography.
• Form: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.