AKAP7 (A-kinase Anchor Protein 7 Isoform gamma, A kinase (PRKA) Anchor Protein 7), Rabbit

Catalog Number: USB-474994
Article Name: AKAP7 (A-kinase Anchor Protein 7 Isoform gamma, A kinase (PRKA) Anchor Protein 7), Rabbit
Biozol Catalog Number: USB-474994
Supplier Catalog Number: 474994
Alternative Catalog Number: USB-474994-100
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Application: WB
Immunogen: Synthetic peptide corresponding to the middle region of human AKAP7
AKAP7 is a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 057461
UniProt: Q9P0M2
Purity: Purified by Protein A affinity chromatography.
Form: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.