ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2, Ectonucleotide Pyrophosphatase/Phosphodiesterase 2), Rabbit
Catalog Number:
USB-480215
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| Article Name: | ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2, Ectonucleotide Pyrophosphatase/Phosphodiesterase 2), Rabbit |
| Biozol Catalog Number: | USB-480215 |
| Supplier Catalog Number: | 480215 |
| Alternative Catalog Number: | USB-480215-100 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Immunogen: | Synthetic peptide corresponding to the N-terminal region of human ENPP2 |
| The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5 end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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