GCLM (Glutamate Cysteine Ligase Regulatory Subunit, Glutamate Cysteine Ligase, Modifier Subunit), Rabbit

Catalog Number: USB-481681
Article Name: GCLM (Glutamate Cysteine Ligase Regulatory Subunit, Glutamate Cysteine Ligase, Modifier Subunit), Rabbit
Biozol Catalog Number: USB-481681
Supplier Catalog Number: 481681
Alternative Catalog Number: USB-481681-100
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Application: IHC, WB
Immunogen: Synthetic peptide corresponding to the middle region of human GCLM
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Applications: Suitable for use in Immunohistochemistry, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 002052
UniProt: P48507
Purity: Purified by affinity chromatography.
Form: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.