MED7 (Mediator of RNA Polymerase II Transcription Subunit 7, Mediator Complex Subunit 7), Rabbit
Catalog Number:
USB-485668
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| Article Name: | MED7 (Mediator of RNA Polymerase II Transcription Subunit 7, Mediator Complex Subunit 7), Rabbit |
| Biozol Catalog Number: | USB-485668 |
| Supplier Catalog Number: | 485668 |
| Alternative Catalog Number: | USB-485668-100 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ChIP, WB |
| Immunogen: | Synthetic peptide corresponding to the middle region of human MED7 |
| The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. Applications: Suitable for use in Western Blot, CHIP. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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