SLC7A5 (Large Neutral Amino Acids Transporter Small Subunit 1, Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5), Rabbit
Catalog Number:
USB-492190
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| Article Name: | SLC7A5 (Large Neutral Amino Acids Transporter Small Subunit 1, Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5), Rabbit |
| Biozol Catalog Number: | USB-492190 |
| Supplier Catalog Number: | 492190 |
| Alternative Catalog Number: | USB-492190-100 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| SLC7A5 is a sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. SLC7A5 is involved in cellular amino acid uptake. SLC7A5 acts as an amino acid exchanger. SLC7A5 is involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. SLC7A5 plays a role in neuronal cell proliferation (neurogenesis) in brain. SLC7A5 is involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. SLC7A5 is involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. SLC7A5 may play an important role in high-grade gliomas. SLC7A5 mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. SLC7A5 acts as the major transporter of tyrosine in fibroblasts. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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