CD200, Recombinant, Mouse, aa31-232, His-Tag

Article Name:	CD200, Recombinant, Mouse, aa31-232, His-Tag
Biozol Catalog Number:	USB-497023
Supplier Catalog Number:	497023
Alternative Catalog Number:	USB-497023-10,USB-497023-20,USB-497023-50,USB-497023-100,USB-497023-250
Manufacturer:	US Biological
Category:	Molekularbiologie

CD200, also known as OX-2 membrane glycoprotein isoform 1, is one of the immunoglobulin superfamily. It plays an important role in anti-tumor immunity through interaction with its receptor, and overexpression of this protein effects on malignancies as well as on cancer stem cells. In T cells, this protein functions as a costimulatory effect that is independent of the CD28 pathway. It also plays an important role on myeloid cell regulation that is suggested by restricted expression of its receptor. Studies of this protein in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Recombinant protein corresponding to aa31-232 from mouse CD200, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~23.5kD Biological Activity: Measured by its binding ability in a functional ELISA with Mouse CD200 R1 Amino Acid Sequence: QVEVVTQDER KALHTTASLR CSLKTSQEPL IVTWQKKKAV SPENMVTYSK THGVVIQPAY KDRINVTELG LWNSSITFWN TTLEDEGCYM CLFNTFGSQK VSGTACLTLY VQPIVHLHYN YFEDHLNITC SATARPAPAI SWKGTGTGIE NSTESHFHSN GTTSVTSILR VKDPKTQVGK EVICQVLYLG NVIDYKQSLD KG Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:	23.521
NCBI:	034948
UniProt:	O54901
Purity:	95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL)
Form:	Supplied as a liquid in PBS, pH 7.4, 10% glycerol.