CD299, Recombinant, Human, aa72-399, hIgG-His-Tag

Product Overview

• Article Name: CD299, Recombinant, Human, aa72-399, hIgG-His-Tag
• Biozol Catalog Number: USB-497024
• Supplier Catalog Number: 497024
• Alternative Catalog Number: USB-497024-10,USB-497024-20,USB-497024-50,USB-497024-100,USB-497024-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

CD299, as known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to CD209/DC-SIGN, an HIV gp120-binding protein. This protein is probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. It may mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. CD299 is a receptor for ICAM3, binding to mannose-like carbohydrates. It also recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. Recombinant protein corresponding to aa72-399 from human CD299, fused to hIgG-His-tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~64.8kD Amino Acid Sequence: VSKVPSS LSQEQSEQDA IYQNLTQLKA AVGELSEKSK LQEIYQELTQ LKAAVGELPE KSKLQEIYQE LTRLKAAVGE LPEKSKLQEI YQELTRLKAA VGELPEKSKL QEIYQELTRL KAAVGELPEK SKLQEIYQEL TELKAAVGEL PEKSKLQEIY QELTQLKAAV GELPDQSKQQ QIYQELTDLK TAFERLCRHC PKDWTFFQGN CYFMSNSQRN WHDSVTACQE VRAQLVVIKT AEEQNFLQLQ TSRSNRFSWM GLSDLNQEGT WQWVDGSPLS PSFQRYWNSG EPNNSGNEDC AEFSGSGWND NRCDVDNYWI CKKPAACFRD E Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 64.857
• NCBI: 055072
• UniProt: Q9H2X3
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol