CD47, Recombinant, Human, aa19-141, His-Tag

Product Overview

• Article Name: CD47, Recombinant, Human, aa19-141, His-Tag
• Biozol Catalog Number: USB-497027
• Supplier Catalog Number: 497027
• Alternative Catalog Number: USB-497027-10,USB-497027-20
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

CD47, also known as leukocyte surface antigen CD47 isoform 1, has a role in both cell adhesions by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Recombinant protein corresponding to aa19-141 from human CD47, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~14.7kD Biological Activity: Measured by its binding ability in a functional ELISA with Human SIRP gamma/CD172g Amino Acid Sequence: QLLFNKTKSV EFTFCNDTVV IPCFVTNMEA QNTTEVYVKW KFKGRDIYTF DGALNKSTVP TDFSSAKIEV SQLLKGDASL KMDKSDAVSH TGNYTCEVTE LTREGETIIE LKYRVVSWFS PNE Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 14.7129
• NCBI: 001768
• UniProt: Q08722
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL).
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol