CD9, Recombinant, Human, aa112-195, hIgG-His-Tag

Product Overview

• Article Name: CD9, Recombinant, Human, aa112-195, hIgG-His-Tag
• Biozol Catalog Number: USB-497029
• Supplier Catalog Number: 497029
• Alternative Catalog Number: USB-497029-10,USB-497029-20,USB-497029-100,USB-497029-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant protein corresponding to aa112-195 from human CD9, fused to hIgG-His-tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~36.9kD Amino Acid Sequence: SHKDEVI KEVQEFYKDT YNKLKTKDEP QRETLKAIHY ALNCCGLAGG VEQFISDICP KKDVLETFTV KSCPDAIKEV FDNKFHI Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 36.9326
• NCBI: 001760
• UniProt: P21926
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL).
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol