Chemokine (C-C motif) Ligand 2 (CCL2), Recombinant, Rat, aa24-148, His-Tag

Article Name:	Chemokine (C-C motif) Ligand 2 (CCL2), Recombinant, Rat, aa24-148, His-Tag
Biozol Catalog Number:	USB-497031
Supplier Catalog Number:	497031
Alternative Catalog Number:	USB-497031-10,USB-497031-20,USB-497031-50,USB-497031-100,USB-497031-250
Manufacturer:	US Biological
Category:	Molekularbiologie

Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It binds to chemokine receptors CCR2 and CCR4. It also induces enzyme and cytokine release by monocytes, NK cells and lymphocytes, and histamine release by basophils, primarily due to interaction with CCR2 receptors on these cells. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. Recombinant protein corresponding to aa24-148 from rat Chemokine (C-C motif) Ligand 2 (CCL2), fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~15.1kD Amino Acid Sequence: QPDAVNA PLTCCYSFTG KMIPMSRLEN YKRITSSRCP KEAVVFVTKL KREICADPNK EWVQKYIRKL DQNQVRSETT VFYKIASTLR TSAPLNVNLT HKSEANASTL FSTTTSSTSV EVTSMTEN Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:	15.1134
NCBI:	113718
UniProt:	P14844
Purity:	90% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL)
Form:	Supplied as a liquid in PBS, pH 7.4, 10% glycerol