IL-5, Recombinant, Canine, aa22-134, His-Tag

Product Overview

• Article Name: IL-5, Recombinant, Canine, aa22-134, His-Tag
• Biozol Catalog Number: USB-497046
• Supplier Catalog Number: 497046
• Alternative Catalog Number: USB-497046-10,USB-497046-20,USB-497046-50,USB-497046-100,USB-497046-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

IL-5, also known as interleukin-5, is a member of the hematopoietin receptor superfamily and is comprised of a cytokine-specific alpha chain and the common beta chain that is shared among these cytokines for signaling. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunoglobulin secretion. It related hematopoietic cytokines that are important for allergic inflammation. It is a lineage-specific cytokine for eosinophilpoiesis and plays an important part in diseases associated with increased eosinophils, such as asthma. Recombinant protein corresponding to aa22-134 from canine IL-5, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~13.9kD Biological Activity: Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range 15ng/ml. Amino Acid Sequence: VENPMNRLVA ETLTLLSTHR TWLIGDGNLM IPTPENKNHQ LCIKEVFQGI DTLKNQTAHG EAVDKLFQNL SLIKEHIERQ KKRCAGERWR VTKFLDYLQV FLGVINTEWT PES Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 13.9119
• NCBI: 001006951
• UniProt: Q95J76
• Purity: 90% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.