KELL, Recombinant, Mouse, aa49-713, His-Tag

Product Overview

• Article Name: KELL, Recombinant, Mouse, aa49-713, His-Tag
• Biozol Catalog Number: USB-497048
• Supplier Catalog Number: 497048
• Alternative Catalog Number: USB-497048-10,USB-497048-20,USB-497048-50,USB-497048-100,USB-497048-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Kell, also known as Kell blood group glycoprotein homolog, is a member of the zinc endopeptidase of the neprilysin (NEP) family. It is an enzyme whose principal known function is the production of a potent bioactive peptide, ET-3. It also includes endothelin converting enzymes (ECE-1 and ECE-2), PEX, XCE, DINE and several NEP-like proteins. It is linked through a single disulfide bond to XK, a putative membrane transporter. The two proteins constitute the Kell blood group antigens. The Kell antigen system (also known as Kell-Cellano system) is one of the most clinically important blood group systems. Recombinant protein corresponding to aa49-713 from mouse KELL, fused to His-tag at C-terminal, expressed in baculovirus. Molecular Weight: ~76.3kD (674aa) Amino Acid Sequence: IFRNCGP CPCETPVCME LLDHYLASGN RSVAPCTDFF SFACEKANGT SDSFQALTEE NKSRLWRLLE APGSWHLGSG EEKAFQFYNS CMDTDAIEAS GSGPLIQIIE ELGGWNITGN WTSLDFNQNL RLLMSQYGHF PFFRAYLRPH PAPPHTPIIQ IDQPEFDILL QQEQEQKVYA QILREYVTYL NRLGTLLGSN PQEAQQHASW SIVFTSRLFQ FLRPQQQQQA QDKLFHVVTI DELQEMAPAI DWLSCLQAIF TPMSLNSSQT LVVHDLDYLR NMSQLVEEGL LNHRESIQSY MILGLVDTLS PALDTKFQEA RRELIQELRK LKERPPLPAY PRWMKCVEQT GAFFEPTLAA LFVREAFGPS IQSAAMELFA EIKDAVIIRL KKLSWISEET QKEALNKLAQ LQVEMGAPKR AVKPDIATQE YNDIQLGPSF LQSFLSCVRS LRARNVQSFL QPFPYHRWQK SPWEVNAYYS ISDHMVVFPA GLLQPPFFHP GYPRAVNFGA AGSIMAHELL HIFYQLLLPG GCPACDTHVL QEALLCLERH YAAFPLPSIS SFNGSHTLLE NAADIGGVAI AFQAYSKRIV EHTGELTLPN LDLSPYQLFF RSYAQVMCRG LSSQDPQDPH SPPSLRVHGP LSNTPDFAKH FHCPRGTLLN PSARCKLW

Product Properties

• Molecular Weight: 76.3674
• NCBI: 115929
• UniProt: Q9EQF2
• Purity: 90% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.