TNFRSF4, Recombinant, Mouse, aa20-211, hIgG-His-Tag

Product Overview

• Article Name: TNFRSF4, Recombinant, Mouse, aa20-211, hIgG-His-Tag
• Biozol Catalog Number: USB-497087
• Supplier Catalog Number: 497087
• Alternative Catalog Number: USB-497087-10,USB-497087-20,USB-497087-50,USB-497087-100,USB-497087-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

TNFRSF4, also known as CD134, is a member of the TNFR-superfamily of receptors. This protein is a receptor for TNFSF4/OX40L/GP34 and a costimulatory molecule implicated in long-term T-cell immunity. OX40-OX40L interactions regulate antigen-specific T-cell expansion and survival, cytokine production. It also modulates cytokine receptor signalling. Therefore the interaction between TNFRSF4 and CD40L plays a key role in the development of multiple imflammatry and autoimmune disease. It has been implicated in the pathologic cytokine storm associated with certain viral infections, including the H5N1 bird flu. Recombinant protein corresponding to aa20-211 from mouse TNFRSF4, fused to hIgG-His-tag at C-terminal, expressed in HEK293 cells. Molecular Weight: ~48.6kD Amino Acid Sequence: VTARRL NCVKHTYPSG HKCCRECQPG HGMVSRCDHT RDTLCHPCET GFYNEAVNYD TCKQCTQCNH RSGSELKQNC TPTQDTVCRC RPGTQPRQDS GYKLGVDCVP CPPGHFSPGN NQACKPWTNC TLSGKQTRHP ASDSLDAVCE DRSLLATLLW ETQRPTFRPT TVQSTTVWPR TSELPSPPTL VTPEGP

Product Properties

• Molecular Weight: 48.6435
• NCBI: 035789
• UniProt: P47741
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.