IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior. Molecular Weight: 190,000 Specific Activity: As Reported Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Donor Consent: The raw material used in the purification of this product has been obtained from an FDA licensed collection center. Further the donor or the donors next of kin has given by signature full informed consent for the material to be used in commercial scientific research, including the sharing, transferring, or selling of samples to third parties involved in this research. The raw material was obtained in an ethical manner in full compliance with national legislation, and the donor identity is held as confidential information by the licensed collection center. Testing: Shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Molecular Weight:
190000
Purity:
95% (SDS-PAGE)
Form:
Supplied as a liquid in 15mM potassium phosphate, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
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