Estradiol 3-(beta-D-Glucuronide) (Sodium Salt), CAS [[14982-12-8]]

Product Overview

• Article Name: Estradiol 3-(beta-D-Glucuronide) (Sodium Salt), CAS [[14982-12-8]]
• Biozol Catalog Number: USB-505265
• Supplier Catalog Number: 505265
• Alternative Catalog Number: USB-505265-1,USB-505265-5,USB-505265-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Estradiol 3-(beta-D-glucuronide) (E23G) is a non-cholestatic regioisomer of the estrogen metabolite, estradiol 17-(beta-D-glucuronide) (E217G).1,2 It acts as a substrate for multidrug resistance protein 2 (MRP2, Km = 122 µM), competing with E217G for MRP2-mediated transport (IC50 = 14.2uM).2,3 E23G has been reported to inhibit E217G transport through rat organic anion-transporting polypeptide 1 with a Ki value of 9.7uM, but is a low-affinity inhibitor of both MRP4 and MRP7 (IC50s = ~100uM).2 Synonyms: (17beta)-17-hydroxyestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronic acid, monosodium salt, E23G, beta-Estradiol 3-(beta-D-Glucuronide), 17beta-Estradiol 3-(beta-D-Glucuronide), 17beta-Oestradiol 3-(beta-D-Glucuronide) CAS No: 14982-12-8 Molecular Formula: C24H31O8Na Molecular Weight: 470.5 Solubility: DMSO: 20mg/ml DMF: >10mg/ml Purity: 95% Appearance: Crystalline solid Storage and Stability: Store at 4C. Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 470.5
• CAS Number: [14982-12-8]