Arylsulfatase A, Recombinant, Mouse, aa18-506, His-Tag (Arsa, As-2, AS-A, As2, ASA, AW212749, TISP73)

Product Overview

• Article Name: Arylsulfatase A, Recombinant, Mouse, aa18-506, His-Tag (Arsa, As-2, AS-A, As2, ASA, AW212749, TISP73)
• Biozol Catalog Number: USB-506163
• Supplier Catalog Number: 506163
• Alternative Catalog Number: USB-506163-10,USB-506163-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Arsa, also known as arylsulfatase A, is a prototype member of the sulfatase family. It is an enzyme that catalyzes the degradation of sulfatides, a glycosphingolipid found in many tissues, but predominantly in myelin and kidney. The serum level of its might be helpful in diagnosis of lung and central nervous system cancer. Description: Recombinant protein corresponding to aa18-506 of mouse Arsa, fused to His-tag at C-terminus, expressed in Baculovirus Molecular Weight: ~ 53.2kD (498aa), ~50-70kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (LAL) Specific Activity: >4,500pmol/min/ug Unit Definition: Defined as the amount of enzyme that hydrolyze 4-Nitrocatechol at pH 5.0, 37C. AA Sequence: ADPSPPNILL IFADDLGYGD LGSYGHPSST TPNLDQLAEG GLRFTDFYVP VSLCTPSRAA LLTGRLPVRS GMYPGVLGPS SQGGLPLEEV TLAEVLAARG YLTGMAGKWH LGVGPEGAFL PPHQGFHRFL GIPYSHDQGP CQNLTCFPPD IPCKGGCDQG LVPIPLLANL TVEAQPPWLP GLEARYVSFS RDLMADAQRQ GRPFFLYYAS HHTHYPQFSG QSFTKRSGRG PFGDSLMELD GAVGALMTTV GDLGLLEETL VIFTADNGPE LMRMSNGGCS GLLRCGKGTT FEGGVREPAL VYWPGHITPG VTHELASSLD LLPTLAALTG APLPNVTLDG VDISPLLLGT GKSPRKSVFF YPPYPDEIHG VFAVRNGKYK AHFFTQGSAH SDTTSDPACH AANRLTAHEP PLLYDLSQDP GENYNVLESI EGVSPEALQA LKHIQLLKAQ YDAAMTFGPS QIAKGEDPAL QICCQPSCTP HPVCCHCPGS QSHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• NCBI: 033843
• UniProt: P50428
• Purity: >95% (SDS-PAGE)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.