IFNA7, Recombinant, Human, aa24-189, His-Tag (Interferon alpha-7)

Catalog Number: USB-506180
Article Name: IFNA7, Recombinant, Human, aa24-189, His-Tag (Interferon alpha-7)
Biozol Catalog Number: USB-506180
Supplier Catalog Number: 506180
Alternative Catalog Number: USB-506180-50,USB-506180-250
Manufacturer: US Biological
Category: Molekularbiologie
IFNA7, also known as interferon alpha-7, is a member of the interferon family. Interferon promotes the production of two enzymes, protein kinase and oligoadenylate synthetase. They allow the cells to communicate with the protective barrier of the immune system to eradicate pathogens or tumors. IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. IFN-alpha has both anti-viral and immunomodulatory activities on target cells, and increases the awareness of infection or tumor cells by elevating antigen presentation to T lymphocytes. This protein has both anti-viral and immunomodulatory activities on target cells and involved both in ligand binding and signal transduction. Recombinant protein corresponding to aa24-189 of human IFNA7, fused to His-tag at C-terminus, expressed in Baculovirus. Molecular Weight: ~20.7kD (175aa), ~18-28kD (SDS-PAGE under reducing conditions) Amino Acid Sequence: ADPCDLPQTH SLRNRRALIL LAQMGRISPF SCLKDRHEFR FPEEEFDGHQ FQKTQAISVL HEMIQQTFNL FSTEDSSAAW EQSLLEKFST ELYQQLNDLE ACVIQEVGVE ETPLMNEDFI LAVRKYFQRI TLYLMEKKYS PCAWEVVRAE IMRSFSFSTN LKKGLRRKDH HHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 20.7
NCBI: 066401
UniProt: P01567
Purity: 90% (SDS-PAGE). Endotoxin: 1EU/ug (LAL).
Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.