Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.1 It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.2 Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) beta-strand (PrP (110-136)).3 Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM. Synonyms: n-Dodecylphosphocholine, dodecyl 2-(trimethylammonio)ethyl phosphate, 2-[[(dodecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium, inner salt, DPC, Fos-Choline-12 CAS No: 29557-51-5 Molecular Formula: C17H38NO4P Molecular Weight: 351.46 Appearance: Crystalline solid Purity: 95% Solubility: Ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of dodecylphosphocholine in ethanol is approximately 15mg/ml and approximately 16mg/ml in DMSO and DMF. Storage: -20C
Molecular Weight:
351.46
Purity:
95%
Form:
Crystalline solid
CAS Number:
[29557-51-5]
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