Cathepsin X/Z/P, Recombinant, Human, aa24-303 His-Tag
Catalog Number:
USB-532272
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| Article Name: | Cathepsin X/Z/P, Recombinant, Human, aa24-303 His-Tag |
| Biozol Catalog Number: | USB-532272 |
| Supplier Catalog Number: | 532272 |
| Alternative Catalog Number: | USB-532272-50,USB-532272-100 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| Cathepsin Z, also known Cathepsin X and Cathepsin P, is a member of the C1 family of lysosomal cysteine proteases. It exhibits carboxy-monopeptidase and carboxy-dipeptidase activity. This protein regulates maturation of dendritic cells and plays important role in the initiation of adaptive immunity. It is also involved in tumor and immune cells as higher expression is found in tumor and immune cells of prostate and gastric carcinomas and inmacrophages of gastric mucosa. Recombinant protein corresponding to aa24-303 from human Cathepsin Z, fused to His-Tag at C-terminal expressed in Baculovirus. Molecular Weight: ~32.5kD (288aa) Specific Activity: >1,400 pmol/min/ug Unit Definition: One unit will convert 1.0 pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH/minute at pH 3.5 at 25C. Amino Acid Sequence: GLYFRRGQTC YRPLRGDGLA PLGRSTYPRP HEYLSPADLP KSWDWRNVDG VNYASITRNQ HIPQYCGSCW AHASTSAMAD RINIKRKGAW PSTLLSVQNV IDCGNAGSCE GGNDLSVWDY AHQHGIPDET CNNYQAKDQE CDKFNQCGTC NEFKECHAIR NYTLWRVGDY GSLSGREKMM AEIYANGPIS CGIMATERLA NYTGGIYAEY QDTTYINHVV SVAGWGISDG TEYWIVRNSW GEPWGERGWL RIVTSTYKDG KGARYNLAIE EHCTFGDPIV LEHHHHHH Applications: Suitable for use in Enzyme Activity and SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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