IL31, also known as interleukin-31, is a cytokine with an anti-parallel four-helix bundle structure in the gp130/IL-6 cytokine family. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. This protein is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2). This protein is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. Recombinant protein corresponding to aa24-156 from Canine IL31, expressed in Baculovirus. Molecular Weight: ~15.3kD (136aa) Amino Acid Sequence: SHMAPTHQLP PSDVRKIILE LQPLSRGLLE DYQKKETGVP ESNRTLLLCL TSDSQPPRLN SSAILPYFRA IRPLSDKNII DKIIEQLDKL KFQHEPETEI SVPADTFECK SFILTILQQF SACLESVFKS LNSGPQ Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.