CD38, Recombinant, Human, aa43-300, Avi-His-Tag

Catalog Number: USB-544229
Article Name: CD38, Recombinant, Human, aa43-300, Avi-His-Tag
Biozol Catalog Number: USB-544229
Supplier Catalog Number: 544229
Alternative Catalog Number: USB-544229-100
Manufacturer: US Biological
Category: Molekularbiologie
CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+ , and ADP-ribose 3. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells 1, 4. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells 5, 6. Source: Recombinant protein corresponding to aa43-300 from human CD38, fused to Avi-His-Tag at C-terminal, expressed in HEK293 cells. Molecular Weight: ~33kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight: 33
NCBI: 001775
UniProt: P28907
Purity: 90%
Form: Supplied as a liquid in PBS, pH 7.4, 20% glycerol.