CD38, Recombinant, Human, aa43-300, His-Tag, (PE)

Product Overview

• Article Name: CD38, Recombinant, Human, aa43-300, His-Tag, (PE)
• Biozol Catalog Number: USB-544232
• Supplier Catalog Number: 544232
• Alternative Catalog Number: USB-544232-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+ , and ADP-ribose 3. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells 1, 4. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells 5, 6. Source: Recombinant protein corresponding to aa43-300 from human CD38, fused to His-Tag at C-terminal, expressed in HEK293 cells. Molecular Weight: ~31kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• Molecular Weight: 31
• NCBI: 001775
• UniProt: P28907
• Purity: 90%
• Form: Supplied as a liquid in PBS, pH 7.4, 20% glycerol. Labeled with R-Phycoerythrin (PE).