Placental Lactogen, Recombinant, Human, aa27-217, His-Tag

Product Overview

• Article Name: Placental Lactogen, Recombinant, Human, aa27-217, His-Tag
• Biozol Catalog Number: USB-552174
• Supplier Catalog Number: 552174
• Alternative Catalog Number: USB-552174-50,USB-552174-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

CSH1, also known as placental lactogen, is a member of the PRL/GH family. CSH1 gene is located on chromosome 17q which participates in the regulation of postnatal and intrauterine growth. This protein is produced only during preganancy and plays important role in increase of pancreatic islets. It also inhibits apoptosis of insulinoma cell lines by activating the phosphorylation of AKT protein. CSH1 activates PRLR through zinc-induced dimerization but does not interact with GHR. Source: Recombinant protein corresponding to aa27-217 from human Placental Lactogen/CSH1 Protein, fused to His-Tag at C-terminal, expressed in baculovirus. AA Sequence: VQTVPLSRLF DHAMLQAHRA HQLAIDTYQE FEETYIPKDQ KYSFLHDSQT SFCFSDSIPT PSNMEETQQK SNLELLRISL LLIESWLEPV RFLRSMFANN LVYDTSDSDD YHLLKDLEEG IQTLMGRLED GSRRTGQILK QTYSKFDTNS HNHDALLKNY GLLYCFRKDM DKVETFLRMV QCRSVEGSCG F Biological Activity: Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range 0.8ng/ml. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 23.1
• NCBI: 001308
• UniProt: P0DML2
• Purity: 90% (SDS-PAGE). Endotoxin: <1EU/1ug (LAL)
• Form: Supplied as a liquid in PBS, pH 7.4, 30% glycerol