STX11 encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis. Vector Description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. cDNA Size: 864bp Preparation before Usage: 1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid. Nucleotide Sequence: ATGAAAGACCGGCTAGCAGAACTTCTGGACTTGTCCAAGCAATATGACCAGCAGTTCCCAGACGGGGACGATGAGTTTGACTCGCCCCACGAGGACATCGTGTTCGAGACGGACCACATCCTGGAGTCCCTGTACCGAGACATCCGGGACATTCAGGATGAAAACCAGCTGCTGGTGGCCGACGTGAAGCGGCTGGGAAAGCAGAACGCCCGCTTCCTCACGTCCATGCGGCGCCTCAGCAGCATCAAGCGCGACACCAACTCCATCGCCAAGGCCATCAAGGCCCGGGGCGAGGTCATCCACTGCAAGCTGCGCGCCATGAAGGAGCTGAGCGAGGCGGCTGAGGCCCAGCACGGCCCGCACTCGGCAGTGGCGCGCATTTCGCGGGCGCAGTACAACGCGCTCACCCTCACCTTCCAGCGCGCCATGCACGACTACAACCAGGCCGAGATGAAGCAGCGCGACAACTGCAAGATCCGCATCCAGCGCCAGCTGGAGATCATGGGCAAGGAAGTCTCGGGCGACCAGATCGAGGACATGTTCGAGCAGGGTAAGTGGGACGTGTTTTCCGAGAACTTGCTGGCCGACGTGAAGGGCGCGCGGGCCGCCCTCAACGAGATCGAGAGCCGCCACCGCGAACTGCTGCGCCTGGAGAGCCGCATCCGCGACGTACACGAGCTCTTCTTGCAGATGGCGGTGCTGGTGGAGAAGCAGGCCGACACCCTGAACGTCATCGAGCTCAACGTACAAAAGACGGTCGACTACACCGGCCAGGCCAAGGCGCAGGTGCGGAAGGCCGTGCAGTACGAGGAGAAGAACCCCTGCCGGACCCTCTGCTGCTTCTGCTGTCCCTGCCTCAAGTAG Translation Sequence: MKDRLAELLD LSKQYDQQFP DGDDEFDSPH EDIVFETDHI LESLYRDIRD IQDENQLLVA DVKRLGKQNA RFLTSMRRLS SIKRDTNSIA KAIKARGEVI HCKLRAMKEL SEAAEAQHGP HSAVARISRA QYNALTLTFQ RAMHDYNQAE MKQRDNCKIR IQRQLEIMGK EVSGDQIEDM FEQGKWDVFS ENLLADVKGA RAALNEIESR HRELLRLESR IRDVHELFLQ MAVLVEKQAD TLNVIELNVQ KTVDYTGQAK AQVRKAVQYE EKNPCRTLCC FCCPCLK Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
