Early E3 18.5kD Glycoprotein, Recombinant, Human Adenovirus C Serotype 2, aa18-123, His-Tag, Myc-Tag

Product Overview

• Article Name: Early E3 18.5kD Glycoprotein, Recombinant, Human Adenovirus C Serotype 2, aa18-123, His-Tag, Myc-Tag
• Biozol Catalog Number: USB-584342
• Supplier Catalog Number: 584342
• Alternative Catalog Number: USB-584342-20,USB-584342-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface. Also delays the expression of class I alleles that it cannot affect by direct retention. Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes. Source: Recombinant protein corresponding to aa18-123 from human adenovirus C serotype 2 Early E3 18.5kD glycoprotein, fused to 10X His-Tag at N-terminal and Myc-Tag at C-terminal, expressed in E.coli. Molecular Weight: ~20.0kD Amino Acid Sequence: AKKVEFKEPACNVTFKSEANECTTLIKCTTEHEKLIIRHKDKIGKYAVYAIWQPGDTNDYNVTVFQGENRKTFMYKFPFYEMCDITMYMSKQYKLWPPQKCLENTG Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 20
• UniProt: P68978
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.