Leucine-rich Repeat Flightless-interacting Protein 1, Recombinant, Human, aa1-314, His-Tag

Product Overview

• Article Name: Leucine-rich Repeat Flightless-interacting Protein 1, Recombinant, Human, aa1-314, His-Tag
• Biozol Catalog Number: USB-585179
• Supplier Catalog Number: 585179
• Alternative Catalog Number: USB-585179-20,USB-585179-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5-AGCCCCCGGCG-3) and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Source: Recombinant protein corresponding to aa1-314 from human Leucine-rich repeat flightless-interacting protein 1, fused to 6X His-Tag at N-terminal, expressed in E.coli. Molecular Weight: ~40.1kD Amino Acid Sequence: MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQSLSTCSLDR Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 40.1
• UniProt: Q32MZ4
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.