Mannose-binding Protein C, Recombinant, Bovine, aa21-249, Flag-Myc-Tag

Catalog Number: USB-585325
Article Name: Mannose-binding Protein C, Recombinant, Bovine, aa21-249, Flag-Myc-Tag
Biozol Catalog Number: USB-585325
Supplier Catalog Number: 585325
Alternative Catalog Number: USB-585325-20,USB-585325-100
Manufacturer: US Biological
Category: Molekularbiologie
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. Source: Recombinant protein corresponding to aa21-249 from bovine Mannose-binding protein C, fused to Flag-Myc-Tag at N-terminal, expressed in Mammalian cell. Molecular Weight: ~28.9kD Amino Acid Sequence: DTETENCENIRKTCPVIACGPPGINGIPGKDGRDGAKGEKGEPGQGLRGSQGPPGKMGPQGTPGIPGIPGPIGQKGDPGENMGDYIRLATSERATLQSELNQIKNWLIFSLGKRVGKKAFFTNGKKMPFNEVKTLCAQFQGRVATPMNAEENRALKDLVTEEAFLGITDQETEGKFVDLTGKGVTYQNWNDGEPNNASPGEHCVTLLSDGTWNDIACSASFLTVCEFSL Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 28.9
UniProt: O02659
Purity: 90% (SDS-PAGE)
Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.