Pulmonary Surfactant-associated Protein A1, Recombinant, Human, aa21-248, His-Tag

Catalog Number: USB-586069
Article Name: Pulmonary Surfactant-associated Protein A1, Recombinant, Human, aa21-248, His-Tag
Biozol Catalog Number: USB-586069
Supplier Catalog Number: 586069
Alternative Catalog Number: USB-586069-20
Manufacturer: US Biological
Category: Molekularbiologie
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages., (Microbial infection) Recognition of M.tuberculosis by dendritic cells may occur partially via this molecule. Can recognize, bind, and opsonize pathogens to enhance their elimination by alveolar macrophages. Source: Recombinant protein corresponding to aa21-248 from human Pulmonary surfactant-associated protein A1, fused to 6X His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~26.2kD Amino Acid Sequence: EVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 26.2
UniProt: Q8IWL2
Purity: 85% (SDS-PAGE)
Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.