Sclerostin Domain-containing Protein 1, Recombinant, Rat, aa24-206, His-Tag, Myc-Tag

Catalog Number: USB-586241
Article Name: Sclerostin Domain-containing Protein 1, Recombinant, Rat, aa24-206, His-Tag, Myc-Tag
Biozol Catalog Number: USB-586241
Supplier Catalog Number: 586241
Alternative Catalog Number: USB-586241-20
Manufacturer: US Biological
Category: Molekularbiologie
Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. Source: Recombinant protein corresponding to aa24-206 from rat Sclerostin domain-containing protein 1, fused to 10X His-Tag at N-terminal and Myc-Tag at C-terminal, expressed in Yeast. Molecular Weight: ~24.6kD Amino Acid Sequence: FKNDATEILYSHVVKPVSAHPSSNSTLNQARNGGRHFSSTGLDRNSRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESVSPAKPAQHHRERKRASKSSKHSLS Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 24.6
UniProt: Q642G2
Purity: 85% (SDS-PAGE)
Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.