TGF-beta-activated Kinase 1 and MAP3K7-binding Protein 2, Recombinant, Human, aa401-693, His-Tag, Myc-Tag

Product Overview

• Article Name: TGF-beta-activated Kinase 1 and MAP3K7-binding Protein 2, Recombinant, Human, aa401-693, His-Tag, Myc-Tag
• Biozol Catalog Number: USB-586483
• Supplier Catalog Number: 586483
• Alternative Catalog Number: USB-586483-20
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of Lys-63-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at Thr-187. Involved in heart development. Source: Recombinant protein corresponding to aa401-693 from human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, fused to 10X His-Tag at N-terminal and Myc-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~37.1kD Amino Acid Sequence: MRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQKARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSIIKTPKTQDTEDDEGAQWNCTACTFLNHPALIRCEQCEMPRHF Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 37.1
• UniProt: Q9NYJ8
• Purity: 85% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.