Inhibin beta A Chain, Active, Recombinant, Human, aa311-426 (INHBA)

Catalog Number: USB-586921
Article Name: Inhibin beta A Chain, Active, Recombinant, Human, aa311-426 (INHBA)
Biozol Catalog Number: USB-586921
Supplier Catalog Number: 586921
Alternative Catalog Number: USB-586921-10, USB-586921-50
Manufacturer: US Biological
Category: Molekularbiologie
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Recombinant protein corresponding to aa311-426 from human Inhibin beta A chain, expressed in Mammalian cell. Molecular Weight: ~13kD Biological Activity: The ED50 as determined by its ability to binding Activin IIB used funtional ELISA is 26.3ug/ml when Activin A 1ug/ml in a solid phases. Amino Acid Sequence: GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 13
UniProt: P08476
Purity: 95% (SDS-PAGE) Endotoxin: 1EU/ug (LAL)
Form: Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with sterile ddH2O, to a concentration of 0.1-1mg/ml.