Salinamide A is a rare depsipeptide first reported as a metabolite of a marine actinomycete by Trischman and coworkers, Scripps Institute of Oceanography, USA in 1994. Salinamide A has antiinflammatory and antibacterial activity. Salinamide A inhibits bacterial RNA polymerase, by binding to the RNAP bridge-helix cap and preventing conformational changes of the bridge-helix N-terminal hinge necessary for nucleotide addition. Salinamides were patented in 2017 as antibacterial agents. Source: Streptomyces sp. CAS No: 152340-22-2 Molecular Formula: C51H69N7O15 Molecular Weight: 1020.1 Appearance: White solid Solubility: Methanol, DMSO. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with methanol or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight:
1020.1
CAS Number:
[152340-22-2]
* VAT and and shipping costs not included. Errors and price changes excepted
